Milk (Yes, milk) and Parkinson’s disease


We have previously written about the enormous contribution that the ‘Honolulu Heart Study’ has made to our understanding of Parkinson’s disease. This longitudinal study of 8006 “non-institutionalized men of Japanese ancestry, born 1900-1919, resident on the island of Oahu” has provided some with amazing insight to this condition by  allowing us to go back and look at what variables were apparent before people were diagnosed with Parkinson’s disease (Click here to read that post).

Earlier this year, some researchers associated with the study reported an interesting observation.

It involved milk.

In today’s post, we’ll discuss what milk might taught us about Parkinson’s disease.


United Providers of Milk. Source: RSPB

In essence, milk is a pale liquid extracted from the mammary glands of mammals.

Riveting stuff, huh?

Ever since glandular skin secretions began with the evolutionary precursors to mammals – the synapsids – milk has remained the primary source of nutrition for infants. In addition to providing sustenance during early life, however, milk also contains colostrum which transfers elements of the mother’s own immune system (specifically antibodies) to the offspring. This exchange gives junior some extra help in strengthening their own developing immune system.


The synapsids family – proto mammals. Source: Feenixx

As infants grow, there is the process of weaning which gradually introduces the infant to a proper diet and reduces the need for the mother’s milk.


A proper diet. Source: Huffington Post

Now this basic idea of milk sustaining and aiding infants worked just fine until about 10,000 years ago, when we humans began doing something rather different:

We began drinking the milk from other mammals.

Sounds disgusting when you write it like that, I know, but between 7000-9000 years ago in south west Asia humans began drinking a lot more milk. Initially sheep’s milk, as it wasn’t until the 14th century that cow’s milk actually became more popular. But today there are more than 250 million cow producing milk for a dairy consuming population of over 6 billion people (despite the fact that milk can be be made in a laboratory – read more here: Cow-less milk).

Drinking milk certainly has it’s benefits:

  • one of the best sources of calcium for the body.
  • filled with Vitamin D that helps the body absorb calcium.
  • contributes to stronger and healthier bones/teeth
  • rehydration

But have you ever considered whether there is any downside to drinking milk?

Because there are.

For example, drinking too much milk can impair a child’s ability to absorb iron and given that milk has virtually no iron in it, this can result in increased risk of iron deficiency.

And then, of course, there is that thing that the Honolulu Heart Study told us about milk and Parkinson’s disease.

What did the Honolulu Heart Study tell us about milk and Parkinson’s disease?

The Honolulu Heart Study – a longitudinal study of “non-institutionalized men of Japanese ancestry, born 1900-1919, resident on the island of Oahu” –  began in October 1965. In all, 8,006 participants were studied and followed for the rest of their lives (Click here for more on this). 128 of the 8006 individuals enrolled in the study went on to develop Parkinson’s disease, and when the researchers went back and looked at the detail of their lives, they noticed something interesting about milk.


Title: Consumption of milk and calcium in midlife and the future risk of Parkinson disease
Authors: Park M, Ross GW, Petrovitch H, White LR, Masaki KH, Nelson JS, Tanner CM, Curb JD, Blanchette PL, Abbott RD.
Journal: Neurology. 2005 Mar 22;64(6):1047-51.
PMID: 15781824

The researcher found that the incidence of Parkinson’s disease increased with milk intake. In fact, it jumped from 6.9/10,000 person-years in men who consumed no milk to 14.9/10,000 person-years in men who consumed >16 oz/day (approx. 1/2 a litre; p = 0.017). This result suggested that drinking a large cup of milk per day doubled your chances of developing Parkinson’s disease. The researchers noted that this effect was independent of calcium intake. Calcium (from both dairy and nondairy sources) inferred no increase/decrease in the risk of developing Parkinson’s disease. The effect was specific to milk.

Has anyone replicated this finding?

Unfortunately, yes. Two independent groups have found similar results:


Title: Consumption of dairy products and risk of Parkinson’s disease.
Authors: Chen H, O’Reilly E, McCullough ML, Rodriguez C, Schwarzschild MA, Calle EE, Thun MJ, Ascherio A.
Journal: Am J Epidemiol. 2007 May 1;165(9):998-1006.
PMID: 17272289               (This article is OPEN ACCESS if you would like to read it)

These researchers looked at the subjects (57,689 men and 73,175 women) enrolled in the American Cancer Society’s Cancer Prevention Study II Nutrition Cohort, and found a total of 250 men and 138 women with Parkinson’s disease. Dairy product consumption was positively associated with risk of Parkinson’s disease, 1.8 times that of normal in men and 1.3 times in women. When the dairy products were divided into milk, cheese, yogurt and ice cream, only milk remained significantly associated with an increased risk of developing Parkinson’s disease. 


Title: Dietary and lifestyle variables in relation to incidence of Parkinson’s disease in Greece.
Authors: Kyrozis A, Ghika A, Stathopoulos P, Vassilopoulos D, Trichopoulos D, Trichopoulou A.
Journal: Eur J Epidemiol. 2013 Jan;28(1):67-77.
PMID: 23377703

In this third study, the researchers conducted a population-based prospective cohort study involving 26,173 participants in the EPIC-Greece cohort. After analysing their data the investigators also found a strong positive association between the consumption of milk and Parkinson’s disease. And like the previous study, there was no association with cheese or yoghurt. The effect was again specific to milk.

So what is there something in particular in milk causing this effect?

That is the assumption, but we are not clear on what it is exactly. There is some new evidence, however, hinting that certain contaminants.

And this brings us to the research report from earlier this year:


Title: Midlife milk consumption and substantia nigra neuron density at death
Authors: Abbott RD, Ross GW, Petrovitch H, Masaki KH, Launer LJ, Nelson JS, White LR, Tanner CM.
Journal: Neurology. 2016 Feb 9;86(6):512-9.
PMID: 26658906

In this study, the researchers looked at the milk intake data for 449 men in the Honolulu Heart Study (which were collected from 1965 to 1968), and then conducted postmortem examinations of their brains (between 1992 to 2004). The researchers found that subjects who drank more than 2 cups of milk per day during their midlife years had approximately 40% fewer dopamine neurons (in certain areas of a region called the substantia nigra where the dopamine neurons live).

But here is the interesting twist in the story:

None of these 449 subjects were diagnosed with Parkinson’s disease

These were all neurologically normal/healthy individuals.

Plus this particular effect was only observed among the milk drinking, non-smokers. The milk drinking smokers did not have this cell loss (smoking is associated with a reduced risk of developing Parkinson’s disease – click here for more on this).

The researchers then took the study a step further. They  noticed that the cell loss effect was also associated with the presence of heptachlor epoxide in the brain.

What is heptac..whatever?

Heptachlor is an organochlorine compound that was used as an insecticide. Pesticides and insecticides have long been associated with increased risk of Parkinson’s disease (click here to read that post).

In this study, of the 116 brains analysed, heptachlor epoxide was found in 90% of the non-smokers who drank the most milk, but only 63% of those subjects who drank no milk. This lead the researchers to speculate as to whether contamination of milk by heptachlor epoxide could have caused the cell loss. We should point out here that this particular part of the analysis is a wee bit flimsy. The sample size for the non-smoking, high milk consumption group was very small: only 12 individuals.

So what does it all mean?

It means I am now dairy free.

EDITORIAL NOTE HERE: While we do not expect this post to crash the world wide milk market, we did not want to frighten any readers out of their habit of drinking milk. It should be noted here that the daily intake of milk associated with increased risk of Parkinson’s disease is very high (>16 oz/day or 1/2 a litre/day). Having said that lowering ones dairy intake does have many benefits for ones health.

In addition, in our last post, we discussed the microbiome of the gut and how the bacteria there could be influencing Parkinson’s disease. It would be interesting to see whether follow-up studies of that particular study highlight any insecticide/pesticide interactions with the bacteria of the gut.

One last thing: The purpose of today’s post was not to scare people out of drinking milk, but merely to throw a curious observation out there for people to think about. It will be interesting to hear what people think about this, especially any observations based on their own experience.


The banner for today’s post was sourced from AndFarAway

12 thoughts on “Milk (Yes, milk) and Parkinson’s disease

  1. Clearly any effect that drinking milk may have is just one factor in a complicated interplay of factors in Parkinson’s. That said, my husband, who now has Parkinson’s, has told the story many times about how his grandmother who raised him encouraged (and sometimes demanded) that he drink a *gallon* of milk a day, every day, his entire childhood. She had little formal education but wanted to make sure he grew up “big and tall”. (She succeeded in that – he grew to be 6’3″). He also lived for several childhood years in a small farmhouse surrounded by plowed fields – literally almost up to the walls of the house – so there were plenty of other opportunities for pesticide exposure, I’m sure. We’ll never know what role any of this played, but I do wonder.


  2. June 2017 study seems to say low fat milk is the PD culprit, not regular milk –

    “Researchers examined what kinds of dairy each person consumed, including milk, cream, cheese, yogurt, ice cream, butter, margarine and sherbet. They then looked at whether full-fat dairy, as whole milk, was associated with a risk of Parkinson’s disease; there was no association. However, those who consumed at least three servings of low-fat dairy a day had a 34 percent greater chance of developing Parkinson’s than people who consumed less than one serving per day. The researchers also found that when looking specifically at skim and low-fat milk consumption, there was a 39 percent greater chance of developing Parkinson’s for people who consumed more than one serving per day compared to those who consumed less than one serving per week. Eating sherbet or frozen yogurt also was linked to a modest increased risk.”
    Read more at:

    I wonder – is milk bad for those who already have PD?


  3. Two questions:
    1. A study using strictly whole organic milk might be helpful to compare.
    2. A study using whole A2 milk (which is also organic) might be helpful to compare. (A2 is easier to digest and has more protein and more fat.)


    1. Hi Linda,
      Thanks for the comment and interesting questions. I agree that an organic comparison would be interesting, but I am not sure if that information exists in any of the data sets currently available.
      As for A2 milk (Yay! A NZ company produces this stuff), I have lost track of what the research says about A2 so I can’t really comment on this. I am unaware of any research regarding A1/2 milk and Parkinson’s disease. When the use of A2 becomes more widespread it would be interesting to see if it has any effect. Thanks again for the comment, sorry I can’t provide more information.
      Kind regards,


  4. Excellent article.
    In the 1970’s a researcher who studied the incidence of many diseases worldwide made the observation that humans were virtually the only species who drank milk after infancy and in addition drank another species milk. So that’s a common sense way to look at it. To reject that is to reject mother nature. By the way, I tested 12000 patient with vitamin D levels over 16 years. When I told them that level was too low, in the 20’s or so, it was not uncommon that they would tell me, “But i drink plenty of milk everyday.” There are 10 Units of Vitamin D in a quart of milk. When an adult has a low level, they frequently have to take 5,000 units a day to reach an ideal level.


  5. by the way that researcher who made that observation was Nathan Pritikin, and he was ridiculed by the scientific community and of course the dairy industry.


  6. My mom was diagnosed with PD six years ago. I have been (like most that are impacted by PD) have been studying it.
    I am all for learning more about PD, what might cause it, how to prevent it, or cure it. So studies like the ones listed above are good and helpful.
    However, I believe we can get trapped into living (or wanting to live) in a protective bubble to have a long life. What is a long life if you can not live it? Or another way to ask the question… What is life without pizza, gouda cheese on a turkey sandwich, and warm apple pie a la mode (vanilla ice cream)?
    Well, there are lies and then there are percentages and statistics.
    Percentages and statistics are used all the time to spin things to sound better or worse than they really are.
    Let’s take a look at the numbers in the Oahu study and get some perspective.
    Currently there are ~1 million (as of 2022) people in the US with PD. That is 0.3% of the population.
    In the Oahu study 128 men out of 8006 had PD. This equates to 128/8006 = 0.0159 or 1.6%. This means that 98.4% of the men did not get PD. Also the study showed that of the men that got PD, about half of them had more milk intake (6.9/10,000 person-years (no milk) to 14.9/10,000 person-years (milk).
    So that is a 0.8% decrease in your “chance” to get PD if you drink milk. So your chance of getting PD decreases to 99.2% if you are not a milk drinker.
    This also means that of the men in the Oahu study that did not drink milk were almost three times as likely to have PD over the current population of the USA.
    So when the researchers say that drinking milk “doubles” your chances of getting PD, that sounds like a head line. However, when you look at it in the big picture of (in the case of this study) your chances go from 98.4% chance of not getting PD to 99.2%.
    Let’s do some more comparisons … You have a 17% chance of heart disease. 14.2% chance of cancer. A 0.9% chance of dying is a car crash. According to the National Weather Service, a person has a 1-in-15,300 chance of getting struck by lightning in their lifetime (or a 0.0065% chance).
    In the study that showed a correlation between low dopamine neurons and milk intake is interesting. As a person that suffers from anxiety and depression, I know that drinking milk can help with my mood and calm me down. So perhaps the low dopamine neurons was genetic (some people are more prone to depression and anxiety than others) and can lead to the subject drinking more milk. Bananas are popular with people with anxiety for the same reason – they help the person to relax.
    Thanks for reading,


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.