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The Chinese stem cell trial

Chinese researchers recently published pre-clinical research demonstrating the use of their protocol for generating stem cell-derived neurons for cell transplantation in Parkinson’s.

The data represents the last step/proof-of-principle stage for taking this procedure into clinical trials (which are ongoing).

In today’s post, we will discuss what cell transplantation is, we will review the new data, and we will consider some of the issues associated with taking this procedure to the clinic.



Brain surgery. Source Bionews-tx

As we have discussed before, any ‘cure’ for Parkinson’s requires 3 components:

  1. A disease halting mechanism – slowing or stopping the progression of the condition
  2. A neuroprotective agent – a treatment that will protect and support the remaining cells
  3. Some form of cell replacement therapy – introducing new cells to replace the ones that have been lost

Now, the bad new is that there is no ‘silver bullet’ on the horizon that provides all three (for example, there is no neuroprotective agent that also replaces lost cells).

But the good news is that we have a great deal of clinical research being conducted in all three of these areas. This video provides an overview of just some of the many different ways we are approaching all three components:

Recently a research report focused on a cell transplantation (a form of cell replacement therapy) approach for Parkinson’s was published by a group of researchers in China. They have proposed that the results presented in the report justify their efforts to take this approach forward into clinical testing.

What is cell transplantation?

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