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Neuromodulation of specific circuits in the brain represents a means of adjusting deficits in neural performance and significantly improving quality of life.
Deep brain stimulation has been widely applied to the treatment of Parkinson’s since Alim Benabid first discovered that electrical stimulation of the basal ganglia improves the symptoms of the condition in the late 1980s.
Now researchers are attempting to refine the approach further with new technology (such as optogenetics) and more specific targeting – stimulating only particular types of neurons – with impressive results and potentially immediate implications for treatment.
In today’s post, we will discuss what optogenetics is, review some new preclinical results, and explore those potentially immediate implications for the treatment of Parkinson’s.
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Vienna. Source: Worldofcruising
In 2016, I was lucky enough to be at the “Dopamine” research conference in Vienna (Austria).
It is a wonderful city, the late summer weather was perfect, and an amazing collection of brilliant researchers had gathered to focus on all things dopamine-related for four days. The conference highlighted all the exciting new research being done on this chemical.
There was – of course – a lots of research being presented on Parkinson’s disease as well, given that dopamine plays such a fundamental role in the condition.
And I was sitting in the lecture presentations, listening to all these new results being discussed, thinking how fantastic it all was, when a researcher from Carnegie Mellon University stood up and (without exaggeration) completely – blew – my – mind!
Basically sums my reaction. Source: Canacopegdl
Seriously. I was left speechless by the results presented.
Wow, what were the results???