Tagged: risk factor

Placebo. Nocebo. Gene-cebo?

 

In previous posts, we have discussed some of the potential benefits of knowing your genetic status with regards to Parkinson’s. For example, knowing if you have a certain genetic risk factor could make eligible for taking part in a particular clinical trial.

There may, however, also be some benefits in NOT knowing your genetic status.

New research suggests that simply learning of a genetic risk can alter one’s physiology.

In today’s post, we will review the results of this new research and discuss what it could mean for the Parkinson’s community.

 


Source: LongRoom

When I was a kid, I thought I was superman.

Then one of the adult figures in my life told me that I wasn’t.

And all of a sudden I lost my ability to fly.

Many years have gone by now, and its only recently that I’ve discovered that that person was actually wrong: I am Superman.

Source: Scarymommy

But curiously my powers of levitation have not (yet) returned…

The power of suggestion has always amazed me. Whether it is based on what others tell us, or on what we tell ourselves, it is truly wonderous the enormous impact some of the information we are given has on our lives. We seemingly get told something and quite often it is just accepted as gospel.

Source: izquotes

But as we take in that information, there can also be consequences (perceived or otherwise) resulting from that knowledge. And this can have important implications for us and how we interact with the world. In fact, some information that we absorb can affect our very physiology.

Can you give me an example?

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The genetics of Parkinson’s: New mutants

 

The Parkinson’s research community is currently drowning in data related to genetics.

It feels like every time one comes up for air, there is a new study highlighting not one, but half a dozen novel genetic variants associated with an increased risk of developing the condition. This week alone, a new research report has been made available that by itself proposes 39 new genetic risk factors. 

The researchers analysed the DNA of 37,700 people with Parkinson’s and 1.4 million (!!!) healthy control subjects and found a total of 92 genetic risk factors for PD.

But what does it all mean? How much influence does genetics have on Parkinson’s?

In today’s post, we will outline the genetics of Parkinson’s, review some of the new studies, and discuss what the new findings mean for Parkinson’s.

 


Source: Screenrant

When I say the word ‘mutant’, what do you think of?

Perhaps your imagination drifts towards comic book superheroes or characters in movies who have acquired amazing new super powers resulting from their bodies being zapped with toxic gamma-rays or such like.

Alternatively, maybe you think of certain negative connotation associated with the word ‘mutant’. You might associate the word with terms like ‘weirdo’ or ‘oddity’, and think of the ‘freak show’ performers who used to be put on display at the travelling carnivals.

Circus freak show (photo bombing giraffe). Source: Bretlittlehales

In biology, however, the word ‘mutant’ means something utterly different.

What does ‘mutant’ mean in biology?

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